Birth of mucus
نویسندگان
چکیده
منابع مشابه
Birth of mucus.
THE BIRTH OF MUCUS is one of the most dramatic events in physiology. Fetal mucin develops inside its intracellular membrane-bound womb by polymerization of subunits of protein cores densely decorated with negatively charged oligosaccharides into polymers of as much as 10 Daltons. During gestation, the embryo mucin remains in a tightly folded fetal position, but at the moment of birth when the a...
متن کاملCervical Mucus Properties Stratify Risk for Preterm Birth
BACKGROUND Ascending infection from the colonized vagina to the normally sterile intrauterine cavity is a well-documented cause of preterm birth. The primary physical barrier to microbial ascension is the cervical canal, which is filled with a dense and protective mucus plug. Despite its central role in separating the vaginal from the intrauterine tract, the barrier properties of cervical mucus...
متن کاملBiological modeling of mucus to modulate mucus barriers.
A recent study using a transgenic mouse, whose intestinal mucus contains a molecule made of 12 copies of a domain found in many gelling mucins, demonstrates that it is possible to strengthen mucus properties in situ, leading to promising new treatment strategies in diseases in which the mucosal barrier is impaired.
متن کاملAirway mucus.
Hypersecretion of mucus is a cardinal sign of airways inflammation. Normally, secretion of mucus is designed to protect the respiratory portion of the lung from injury, but in disease its chronic overproduction in large airways (bronchi) and its appearance in small conducting airways (bronchioles) may be detrimental. Its relevance to patient discomfort and infection is generally accepted, but i...
متن کاملAltering Mucus Rheology to “Solidify” Human Mucus at the Nanoscale
The ability of mucus to function as a protective barrier at mucosal surfaces rests on its viscous and elastic properties, which are not well understood at length scales relevant to pathogens and ultrafine environmental particles. Here we report that fresh, undiluted human cervicovaginal mucus (CVM) transitions from an impermeable elastic barrier to non-adhesive objects sized 1 microm and larger...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Physiology-Lung Cellular and Molecular Physiology
سال: 2010
ISSN: 1040-0605,1522-1504
DOI: 10.1152/ajplung.00358.2009